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Calcium Pyruvate

Calcium pyruvate is a naturally occurring compound produced in our body as a result of glucose metabolism. It is most commonly supplemented with as a natural weight loss enhancer, as a means to increase natural energy, as well as provide general health benefits. Despite it being a widely promoted and used supplement, it is wise to review the research on its effectiveness before purchasing it as it may not be worth its weight.

What it does

Calcium pyruvate is most commonly associated with weight loss, the human data on this, however, shows that one should not expect to see major changes on the scale if they are a normal and healthy user[1][2]. Studies in the obese and those with metabolic conditions, however, have shown some results in regards to beneficial weight loss[3][4].

This compound does seem to be somewhat effective at increasing energy or decreasing fatigue[3], which may be beneficial to those on low-calorie diets.

Unfortunately, calcium pyruvate suffers from extremely poor bioavailability and absorption, which may be the reason behind its lackluster effects when studied. This means the ingredient may work as intended, but higher than commonly suggested doses would be required for beneficial results.

How it works

Calcium pyruvate provides its supposed benefits via increases in ATP (adenosine triphosphate) production. When we consume glucose, the body normally goes through a process known as glycolysis where both ATP and pyruvate (in the form of pyruvic acid) are created. This pyruvate still has additional energy in it which can be converted into ATP. By supplementing with calcium pyruvate, you offer your body additional pyruvate that is not required to undergo glycolysis, providing you with larger ATP production capabilities.


The studies which show benefits from calcium pyruvate use it as a replacement for a set percentage of carbohydrates in one’s diet. Although one may think that of course weight loss will happen when total caloric intake is removed, calcium pyruvate does contain calories despite not being a typical food.

For best results, one should eliminate 10-20% of carbohydrates from their diet and replace it with the same amount of grams of calcium pyruvate. This equates to 20-50g per day.